Fig 1: Enrichment plot: HALLMARK_ADIPOGENESIS
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GSE19161_collapsed_to_symbols.GSE19161.cls#EIF4G2 |
| Phenotype | GSE19161.cls#EIF4G2 |
| Upregulated in class | EIF4G2_pos |
| GeneSet | HALLMARK_ADIPOGENESIS |
| Enrichment Score (ES) | 0.20032379 |
| Normalized Enrichment Score (NES) | 0.54436857 |
| Nominal p-value | 0.96184736 |
| FDR q-value | 0.94768965 |
| FWER p-Value | 0.998 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 78 | 0.248 | 0.0313 | Yes |
| 2 | CYP4B1 | CYP4B1 Entrez, Source | cytochrome P450, family 4, subfamily B, polypeptide 1 | 125 | 0.191 | 0.0807 | Yes |
| 3 | PGM1 | PGM1 Entrez, Source | phosphoglucomutase 1 | 156 | 0.154 | 0.1331 | Yes |
| 4 | SLC1A5 | SLC1A5 Entrez, Source | solute carrier family 1 (neutral amino acid transporter), member 5 | 173 | 0.140 | 0.2003 | Yes |
| 5 | CHUK | CHUK Entrez, Source | conserved helix-loop-helix ubiquitous kinase | 243 | 0.082 | 0.1342 | No |
| 6 | APOE | APOE Entrez, Source | apolipoprotein E | 281 | 0.047 | 0.1004 | No |
| 7 | LIFR | LIFR Entrez, Source | leukemia inhibitory factor receptor alpha | 303 | 0.027 | 0.0819 | No |
| 8 | DHRS7 | DHRS7 Entrez, Source | dehydrogenase/reductase (SDR family) member 7 | 353 | -0.005 | -0.0013 | No |
| 9 | GPD2 | GPD2 Entrez, Source | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 358 | -0.010 | -0.0018 | No |
| 10 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 415 | -0.058 | -0.0613 | No |
| 11 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 423 | -0.065 | -0.0289 | No |
| 12 | DDT | DDT Entrez, Source | D-dopachrome tautomerase | 452 | -0.091 | -0.0164 | No |
| 13 | RNF11 | RNF11 Entrez, Source | ring finger protein 11 | 462 | -0.105 | 0.0396 | No |
| 14 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 464 | -0.109 | 0.1123 | No |
| 15 | RIOK3 | RIOK3 Entrez, Source | RIO kinase 3 (yeast) | 485 | -0.129 | 0.1649 | No |
